|
Symbol Name ID |
Whrn
whirlin MGI:2682003 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Abnormal vestibular function |
Absent vestibular function |
Sensorineural hearing impairment |
Hearing impairment |
| Disease(s) Associated with WHRN | ||||
| autosomal recessive nonsyndromic deafness 31 | ||||
| Usher syndrome type 2D |
| Mouse Phenotypes | hearing/vestibular/ear phenotype |
decreased cochlear hair cell number |
abnormal cochlear hair cell stereociliary bundle morphology |
abnormal cochlear hair bundle transient lateral links morphology |
short inner hair cell stereocilia |
abnormal outer hair cell stereociliary bundle morphology |
short outer hair cell stereocilia |
decreased outer hair cell stereocilia number |
short cochlear hair cell stereocilia |
abnormal cochlear inner hair cell morphology |
cochlear inner hair cell degeneration |
abnormal cochlear outer hair cell morphology |
cochlear outer hair cell degeneration |
cochlear hair cell degeneration |
abnormal vestibular hair cell stereociliary bundle morphology |
short vestibular hair cell stereocilia |
abnormal cochlear outer hair cell physiology |
absent cochlear microphonics |
increased or absent threshold for auditory brainstem response |
abnormal auditory summating potential |
abnormal cochlear frequency tuning |
absent cochlear nerve compound action potential |
abnormal distortion product otoacoustic emission |
absent distortion product otoacoustic emissions |
impaired hearing |
deafness |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||
| Whrnhb/Whrnhb | |||||||||||||||||||||||||||
| Whrntm1a(EUCOMM)Wtsi/Whrntm1a(EUCOMM)Wtsi | |||||||||||||||||||||||||||
| Whrntm1b(EUCOMM)Wtsi/Whrntm1b(EUCOMM)Wtsi | * | ||||||||||||||||||||||||||
| Whrntm1Tili/Whrntm1Tili | |||||||||||||||||||||||||||
| Whrnwi/Whrnwi | |||||||||||||||||||||||||||
| Whrnwi/Whrn+ | |||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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