About   Help   FAQ
Symbol
Name
ID
Elane
elastase, neutrophil expressed
MGI:2679229
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Eosinophilia
Neutropenia
Cyclic neutropenia
Congenital agranulocytosis
Monocytosis
Acute monocytic leukemia
Recurrent bacterial infections
Disease(s) Associated with ELANE
cyclic hematopoiesis
severe congenital neutropenia 1

Mouse Phenotypes
immune system phenotype
abnormal neutrophil physiology
impaired neutrophil recruitment
decreased tumor necrosis factor secretion
abnormal inflammatory response
decreased susceptibility to bacterial infection induced morbidity/mortality
increased susceptibility to bacterial infection
increased susceptibility to bacterial infection induced morbidity/mortality
increased susceptibility to infection induced morbidity/mortality
Availability Mouse Genotype
ElaneM1Btlr/ElaneM1Btlr
Elanetm1(cre)Roes/Elanetm1(cre)Roes
Elanetm1Link/Elanetm1Link *
Elanetm1Sds/Elanetm1Sds

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/30/2020
MGI 6.15
The Jackson Laboratory