Symbol Name ID |
Nlrp3
NLR family, pyrin domain containing 3 MGI:2653833 |
Darker colors indicate more annotations |
Human Phenotypes | Splenomegaly |
Hepatosplenomegaly |
Hepatomegaly |
Hernia of the abdominal wall |
Delayed puberty |
Short stature |
Growth delay |
Disease(s) Associated with NLRP3 | |||||||
CINCA Syndrome | |||||||
Muckle-Wells syndrome |
Mouse Phenotypes | increased body fat mass |
decreased body weight |
slow postnatal weight gain |
increased susceptibility to diet-induced obesity |
postnatal growth retardation |
enlarged liver |
increased liver weight |
enlarged spleen |
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Availability | Mouse Genotype | ||||||||
Nlrp3tm1Bhk/Nlrp3tm1Bhk | |||||||||
Nlrp3tm1Wstr/Nlrp3+ | |||||||||
Nlrp3tm3.1Hhf/Nlrp3+ | |||||||||
Nlrp3tm1Hhf/Nlrp3+ Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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Nlrp3tm1Hhf/Nlrp3+ Tg(Zp3-cre)3Mrt/? (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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