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Symbol
Name
ID
Nlrp3
NLR family, pyrin domain containing 3
MGI:2653833
Phenotype annotations related to growth/size/body
Darker colors indicate more annotations
Human Phenotypes
Splenomegaly
Hepatosplenomegaly
Hepatomegaly
Hernia of the abdominal wall
Delayed puberty
Short stature
Growth delay
Disease(s) Associated with NLRP3
CINCA Syndrome
Muckle-Wells syndrome

Mouse Phenotypes
increased body fat mass
decreased body weight
slow postnatal weight gain
increased susceptibility to diet-induced obesity
postnatal growth retardation
enlarged liver
increased liver weight
enlarged spleen
Availability Mouse Genotype
Nlrp3tm1Bhk/Nlrp3tm1Bhk
Nlrp3tm1Wstr/Nlrp3+
Nlrp3tm3.1Hhf/Nlrp3+
Nlrp3tm1Hhf/Nlrp3+
Lyz2tm1(cre)Ifo/Lyz2+  (conditional)
Nlrp3tm1Hhf/Nlrp3+
Tg(Zp3-cre)3Mrt/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory