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Symbol
Name
ID
Pi4ka
phosphatidylinositol 4-kinase alpha
MGI:2448506
Phenotype annotations related to immune system
Darker colors indicate more annotations
Human Phenotypes
Crohn's disease
Disease(s) Associated with PI4KA
hereditary spastic paraplegia 84

Mouse Phenotypes
decreased macrophage apoptosis
increased central memory CD4-positive, alpha-beta T cell number
increased CD4-positive, alpha-beta T cell number
increased alpha-beta T cell number
increased monocyte cell number
abnormal spleen morphology
increased interleukin-1 beta secretion
decreased tumor necrosis factor secretion
Availability Mouse Genotype
Pi4kam1Btlr/Pi4kam1Btlr
Pi4kam2Btlr/Pi4kam2Btlr
Pi4katm1b(EUCOMM)Wtsi/Pi4ka+
Pi4katm2.1Arte/Pi4ka+
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory