Symbol
Name
ID

Megf8
multiple EGF-like-domains 8
MGI:2446294

Phenotype annotations related to limbs/digits/tail

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Genu valgum

Genu varum

Clinodactyly of the 5th finger

Postaxial hand polydactyly

Bilateral postaxial polydactyly

Pseudoepiphyses of the proximal phalanges of the hand

Aplasia/Hypoplasia of the middle phalanges of the hand

Aplasia of the middle phalanx of the hand

Complete duplication of proximal phalanx of the thumb

Broad thumb

Hitchhiker thumb

Deviation of finger

Duplication of the proximal phalanx of the hallux

Preaxial foot polydactyly

Aplasia/Hypoplasia of the middle phalanges of the toes

Toe syndactyly

Polydactyly

Postaxial polydactyly

Preaxial polydactyly

Short digit

Brachydactyly

Syndactyly

Cutaneous finger syndactyly

Finger syndactyly

Coxa valga

Coxa vara

Metatarsus adductus

Talipes equinovarus

Shallow acetabular fossae

Lateral displacement of patellae

Knee flexion contracture

Single transverse palmar crease

Joint contracture of the hand

Disease(s) Associated with MEGF8

Carpenter syndrome

Mouse Phenotypes		limbs/digits/tail phenotype	abnormal autopod morphology	polydactyly	preaxial polydactyly	delayed limb development
Availability	Mouse Genotype	limbs/digits/tail phenotype	abnormal autopod morphology	polydactyly	preaxial polydactyly	delayed limb development
	Megf8^{Gt(G037A09)Wrst}/Megf8^{Gt(G037A09)Wrst}
	Megf8^hlb611/Megf8^hlb611
	Megf8^tm1.1Ddg/Megf8^tm1.1Ddg
	Megf8^tm1.2Ddg/Megf8^tm1.2Ddg H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ (conditional)	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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