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Symbol
Name
ID
Ppargc1b
peroxisome proliferative activated receptor, gamma, coactivator 1 beta
MGI:2444934
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Decreased resting energy expenditure
Disease(s) Associated with PPARGC1B
obesity

Mouse Phenotypes
homeostasis/metabolism phenotype
impaired exercise endurance
impaired adaptive thermogenesis
decreased circulating cholesterol level
decreased circulating free fatty acid level
increased circulating free fatty acid level
decreased circulating triglyceride level
increased circulating triglyceride level
decreased oxygen consumption
insulin resistance
increased liver triglyceride level
decreased triglyceride level
abnormal metabolism
enhanced exercise endurance
Availability Mouse Genotype
Ppargc1btm1.1Avp/Ppargc1btm1.1Avp
Ppargc1btm1.1Dpk/Ppargc1btm1.1Dpk
Ppargc1btm1.1Rev/Ppargc1btm1.1Rev *
Ppargc1btm1Lowl/Ppargc1btm1Lowl
Tg(Ckm-Ppargc1b)T37Brsp/0
Ppargc1btm1.1Javi/Ppargc1btm1.1Javi
Tg(Fabp4-cre)1Rev/?  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
02/05/2019
MGI 6.13
The Jackson Laboratory