Symbol
Name
ID

Chd7
chromodomain helicase DNA binding protein 7
MGI:2444748

Phenotype annotations related to growth/size/body

Darker colors indicate more annotations

Human Phenotypes	Webbed neck	Omphalocele	Umbilical hernia	Delayed puberty	Short stature	Intrauterine growth retardation	Postnatal growth retardation
Disease(s) Associated with CHD7
CHARGE syndrome

Mouse Phenotypes

decreased body fat mass

abnormal olfactory epithelium cilium morphology

abnormal secondary palate development

abnormal palatal shelf fusion at midline

facial asymmetry

decreased palatal rugae number

cleft secondary palate

abnormal internal nares morphology

abnormal olfactory epithelium morphology

abnormal olfactory sensory neuron morphology

decreased olfactory sensory neuron number

eyelid edema

long snout

short snout

abnormal outer ear morphology

embryonic growth retardation

decreased lean body mass

decreased body weight

decreased body length

decreased body size

postnatal growth retardation

Availability

Mouse Genotype

Chd7^em1Jiao/Chd7^em1Jiao

Chd7^Coa1/Chd7⁺

Chd7^Cycn/Chd7⁺

Chd7^Dz/Chd7⁺

Chd7^Edy/Chd7⁺

Chd7^{Gt(S20-7E1)Sor}/Chd7⁺

Chd7^Lda/Chd7⁺

Chd7^Looper/Chd7⁺

Chd7^Mt/Chd7⁺

Chd7^Obt/Chd7⁺

Chd7^Ome/Chd7⁺

Chd7^{tm2a(EUCOMM)Wtsi}/Chd7⁺

Chd7^Todo/Chd7⁺

Chd7^Trooper/Chd7⁺

Chd7^Whi/Chd7⁺

Chd7^em1Kangn/Chd7^em1Kangn
Tg(Prrx1-cre)1Cjt/0 (conditional)

Chd7^em1Kangn/Chd7^em1Kangn
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 (conditional)

Chd7^{tm2c(EUCOMM)Wtsi}/Chd7^{tm2c(EUCOMM)Wtsi}
Tg(Nes-cre)1Kln/0 (conditional)

Chd7^{Gt(S20-7E1)Sor}/Chd7^tm1.1Dmm
Foxg1^tm1(cre)Skm/Foxg1⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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