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Symbol Name ID |
Nipal4
NIPA-like domain containing 4 MGI:2444671 |
| Darker colors indicate more annotations |
| Human Phenotypes | Palmoplantar keratoderma |
Erythroderma |
Hypohidrosis |
Epidermal acanthosis |
Scaling skin |
Dry skin |
Hyperkeratosis |
Congenital nonbullous ichthyosiform erythroderma |
Generalized ichthyosis |
Orthokeratosis |
Parakeratosis |
| Disease(s) Associated with NIPAL4 | |||||||||||
| autosomal recessive congenital ichthyosis 6 |
| Mouse Phenotypes | abnormal keratinocyte differentiation |
impaired skin barrier function |
abnormal corneocyte morphology |
abnormal stratum corneum lipid matrix formation |
hyperkeratosis |
abnormal epidermis stratum granulosum morphology |
abnormal epidermal lamellar body morphology |
abnormal keratohyalin granule morphology |
decreased keratohyalin granule size |
increased keratohyalin granule number |
thick epidermis stratum spinosum |
abnormal skin appearance |
shiny skin |
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| Availability | Mouse Genotype | |||||||||||||
| Nipal4tm1Akih/Nipal4tm1Akih | ||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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