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Symbol
Name
ID
Mcph1
microcephaly, primary autosomal recessive 1
MGI:2443308
Phenotype annotations related to cellular
Darker colors indicate more annotations
Human Phenotypes
Increased rate of premature chromosome condensation
Disease(s) Associated with MCPH1
primary autosomal recessive microcephaly 1

Mouse Phenotypes
abnormal chromosome morphology
abnormal spermatid morphology
decreased male germ cell number
abnormal cell cycle
abnormal mitosis
abnormal mitotic spindle morphology
abnormal male germ cell apoptosis
increased neuron apoptosis
increased cellular sensitivity to gamma-irradiation
abnormal neuron differentiation
abnormal neuronal precursor proliferation
chromosomal instability
induced chromosome breakage
Availability Mouse Genotype
Mcph1Gt(RRO608)Byg/Mcph1Gt(RRO608)Byg
Mcph1tm1.1Zqw/Mcph1tm1.1Zqw
Mcph1tm1.2Kali/Mcph1tm1.2Kali
Mcph1tm1a(EUCOMM)Wtsi/Mcph1tm1a(EUCOMM)Wtsi

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory