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Symbol
Name
ID
Cgas
cyclic GMP-AMP synthase
MGI:2442261
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
abnormal macrophage physiology
decreased circulating interferon-alpha level
decreased circulating interferon-beta level
abnormal dendritic cell physiology
abnormal plasmacytoid dendritic cell physiology
abnormal immune cell physiology
abnormal interferon secretion
increased susceptibility to Herpesvirales infection induced morbidity/mortality
increased susceptibility to Poxviridae infection induced morbidity/mortality
increased susceptibility to Flaviviridae infection induced morbidity/mortality
increased susceptibility to Herpesvirales infection
increased susceptibility to Retroviridae infection
increased susceptibility to Poxviridae infection
increased susceptibility to Flaviviridae infection
Availability Mouse Genotype
Cgastm1a(EUCOMM)Hmgu/Cgastm1a(EUCOMM)Hmgu
Cgastm1d(EUCOMM)Hmgu/Cgastm1d(EUCOMM)Hmgu *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory