Symbol
Name
ID

Lrp4
low density lipoprotein receptor-related protein 4
MGI:2442252

Phenotype annotations related to craniofacial

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Frontal bossing

Thickened calvaria

Micrognathia

Mandibular prognathia

Malar flattening

Macrocephaly

Facial asymmetry

Facial palsy

Prominent forehead

Short philtrum

High, narrow palate

Hypodontia

Abnormal dental enamel morphology

Enamel hypoplasia

Premature loss of permanent teeth

Convex nasal ridge

Short nose

Downslanted palpebral fissures

Ectropion

Disease(s) Associated with LRP4

Cenani-Lenz syndactyly syndrome

sclerosteosis 2

Mouse Phenotypes		craniofacial phenotype	thick neurocranium	abnormal tooth morphology	abnormal incisor morphology	supernumerary incisors	abnormal molar cusp morphology	abnormal tooth development	abnormal enamel morphology
Availability	Mouse Genotype	craniofacial phenotype	thick neurocranium	abnormal tooth morphology	abnormal incisor morphology	supernumerary incisors	abnormal molar cusp morphology	abnormal tooth development	abnormal enamel morphology
	Lrp4^dan/Lrp4^dan	*
	Lrp4^mdig-2J/Lrp4^mdig-2J
	Lrp4^mdig-3J/Lrp4^mdig-3J
	Lrp4^mdig/Lrp4^mdig	*
	Lrp4^mitt/Lrp4^mitt
	Lrp4^mte/Lrp4^mte
	Lrp4^tm1.1Pg/Lrp4^tm1.1Pg
	Lrp4^tm1Her/Lrp4^tm1Her
	Lrp4^tm2Her/Lrp4^tm2Her

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23