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Symbol
Name
ID
Dusp4
dual specificity phosphatase 4
MGI:2442191
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
decreased B cell apoptosis
increased T cell proliferation
increased CD4-positive, alpha beta T cell number
increased IgG1 level
decreased IgG2a level
abnormal macrophage physiology
decreased interferon-gamma secretion
decreased interleukin-10 secretion
increased interleukin-10 secretion
increased interleukin-12 secretion
increased interleukin-13 secretion
increased interleukin-4 secretion
increased interleukin-6 secretion
increased tumor necrosis factor secretion
increased susceptibility to parasitic infection
Availability Mouse Genotype
Dusp4Gt(XG164)Byg/Dusp4Gt(XG164)Byg *
Dusp4tm1Jmol/Dusp4tm1Jmol
Dusp4tm1Plev/Dusp4tm1Plev

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory