|
Symbol Name ID |
Clrn1
clarin 1 MGI:2388124 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Abnormal vestibular function |
Sensorineural hearing impairment |
| Disease(s) Associated with CLRN1 | ||
| Usher syndrome type 3A |
| Mouse Phenotypes | hearing/vestibular/ear phenotype |
absent cochlear inner hair cells |
absent cochlear outer hair cells |
abnormal cochlear hair cell stereociliary bundle morphology |
abnormal inner hair cell stereociliary bundle morphology |
abnormal orientation of outer hair cell stereociliary bundles |
abnormal outer hair cell stereociliary bundle morphology |
abnormal cochlear IHC afferent innervation pattern |
cochlear inner hair cell degeneration |
cochlear outer hair cell degeneration |
degeneration of organ of Corti supporting cells |
organ of Corti degeneration |
abnormal cochlear hair cell physiology |
abnormal cochlear inner hair cell physiology |
decreased cochlear microphonics |
abnormal vestibular hair cell physiology |
abnormal auditory brainstem response |
abnormal auditory brainstem response waveform shape |
increased or absent threshold for auditory brainstem response |
abnormal cochlear nerve compound action potential |
abnormal cochlear nerve fiber response |
increased or absent distortion product otoacoustic emission threshold |
absent distortion product otoacoustic emissions |
impaired hearing |
deafness |
sensorineural hearing loss |
reduced linear vestibular evoked potential |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||
| Clrn1tm1.1(KOMP)Vlcg/Clrn1tm1.1(KOMP)Vlcg | ||||||||||||||||||||||||||||
| Clrn1tm1.1Kuna/Clrn1tm1.1Kuna | * | |||||||||||||||||||||||||||
| Clrn1tm1.1Kuna/Clrn1tm1.1Kuna Tg(Atoh1-Clrn1)#Kuna/0 |
||||||||||||||||||||||||||||
| Clrn1tm1.2Ugpa/Clrn1tm1.2Ugpa | ||||||||||||||||||||||||||||
| Clrn1tm2.1Kuna/Clrn1tm2.1Kuna | ||||||||||||||||||||||||||||
| Clrn1tm2.1Kuna/Clrn1tm2.1Kuna Tg(Atoh1-Clrn1)#Kuna/0 |
||||||||||||||||||||||||||||
| Clrn1tm1.1Ugpa/Clrn1tm1.1Ugpa Myo15atm1.1(cre)Ugds/Myo15a+ (conditional) |
||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/16/2024 MGI 6.23 |
|
|
|
||
Analysis Tools