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Symbol
Name
ID
Dicer1
dicer 1, ribonuclease type III
MGI:2177178
Phenotype annotations related to respiratory system
Darker colors indicate more annotations
Human Phenotypes
Pleuropulmonary blastoma
Disease(s) Associated with DICER1
multinodular goiter
pleuropulmonary blastoma

Mouse Phenotypes
increased mesenchymal cell proliferation involved in lung development
enlarged lung
lung inflammation
abnormal lung development
abnormal branching involved in lung morphogenesis
abnormal lung-associated mesenchyme development
abnormal lung epithelium morphology
small lung lobe
lung cysts
Availability Mouse Genotype
Dicer1tm1Bdh/Dicer1tm1Bdh
Foxp3tm4(YFP/icre)Ayr/Y  (conditional)
Dicer1tm1Bdh/Dicer1tm1Bdh
Foxp3tm4(YFP/icre)Ayr/Foxp3tm4(YFP/icre)Ayr  (conditional)
Dicer1tm1Bdh/Dicer1tm1Bdh
Tg(Foxp3-EGFP/icre)1aJbs/0  (conditional)
Dicer1tm1Bdh/Dicer1tm1Bdh
Shhtm1(EGFP/cre)Cjt/Shh+  (conditional)
Dicer1tm1Mmk/Dicer1tm1Mmk
Shhtm1(EGFP/cre)Cjt/Shh+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/05/2021
MGI 6.16
The Jackson Laboratory