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Symbol
Name
ID

Dicer1
dicer 1, ribonuclease type III
MGI:2177178

Phenotype annotations related to respiratory system

Darker colors indicate more annotations

Human Phenotypes	Pleuropulmonary blastoma
Disease(s) Associated with DICER1	Pleuropulmonary blastoma
multinodular goiter
pleuropulmonary blastoma

Mouse Phenotypes		increased mesenchymal cell proliferation involved in lung development	enlarged lung	lung inflammation	abnormal lung development	abnormal branching involved in lung morphogenesis	abnormal lung-associated mesenchyme development	abnormal lung epithelium morphology	small lung lobe	lung cysts
Availability	Mouse Genotype		enlarged lung	lung inflammation	abnormal lung development	abnormal branching involved in lung morphogenesis	abnormal lung-associated mesenchyme development	abnormal lung epithelium morphology	small lung lobe	lung cysts
	Dicer1^tm1Bdh/Dicer1^tm1Bdh Foxp3^{tm4(YFP/icre)Ayr}/Y (conditional)
	Dicer1^tm1Bdh/Dicer1^tm1Bdh Foxp3^{tm4(YFP/icre)Ayr}/Foxp3^{tm4(YFP/icre)Ayr} (conditional)
	Dicer1^tm1Bdh/Dicer1^tm1Bdh Tg(Foxp3-EGFP/icre)1aJbs/0 (conditional)
	Dicer1^tm1Bdh/Dicer1^tm1Bdh Shh^{tm1(EGFP/cre)Cjt}/Shh⁺ (conditional)
	Dicer1^tm1Mmk/Dicer1^tm1Mmk Shh^{tm1(EGFP/cre)Cjt}/Shh⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 01/05/2021 MGI 6.16