About   Help   FAQ
Symbol
Name
ID
Dicer1
dicer 1, ribonuclease type III
MGI:2177178
Phenotype annotations related to reproductive system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Sertoli cell neoplasm
Testicular seminoma
Ovarian neoplasm
Disease(s) Associated with DICER1
multinodular goiter

Mouse Phenotypes
reproductive system phenotype
abnormal oocyte morphology
azoospermia
oligozoospermia
abnormal male germ cell morphology
abnormal spermatid morphology
decreased male germ cell number
abnormal male germ cell apoptosis
decreased endometrial gland number
decreased ovary weight
abnormal efferent ductules of testis morphology
dilated efferent ductules of testis
Leydig cell hyperplasia
abnormal seminiferous tubule epithelium morphology
abnormal Sertoli cell morphology
ectopic Sertoli cells
small seminiferous tubules
seminiferous tubule degeneration
decreased testis weight
small testis
testis degeneration
abnormal oviduct morphology
short oviduct
abnormal uterus morphology
thin myometrium
short uterine horn
decreased uterus weight
small uterus
abnormal female meiosis
abnormal meiotic spindle morphology
abnormal spermatogenesis
abnormal epididymis morphology
abnormal epididymis epithelium morphology
small epididymis
abnormal oviduct transport
abnormal superovulation
decreased ovulation rate
abnormal pregnancy
failure of embryo implantation
female infertility
male infertility
increased epididymal epithelium cell proliferation
Availability Mouse Genotype
Dicer1em1Psv/Dicer1em1Psv *
Dicer1em2Psv/Dicer1em2Psv *
Dicer1em3Psv/Dicer1em3Psv *
Dicer1tm1Bdh/Dicer1tm1Bdh
Plekha5Tg(AMH-cre)1Flor/0  (conditional)
*
Amhr2tm3(cre)Bhr/Amhr2+
Dicer1tm1Bdh/Dicer1tm1Bdh  (conditional)
*
Defb41tm1(icre)Psip/Defb41+
Dicer1tm1Bdh/Dicer1tm1Bdh  (conditional)
Alpltm1(cre)Nagy/Alpl+
Dicer1tm1.1Mnn/Dicer1tm1.2Mnn  (conditional)
Dicer1tm1.1Mnn/Dicer1tm1.2Mnn
Tg(Zp3-cre)93Knw/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/10/2019
MGI 6.14
The Jackson Laboratory