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Symbol
Name
ID
Dicer1
dicer 1, ribonuclease type III
MGI:2177178
Phenotype annotations related to muscle
Darker colors indicate more annotations
Human Phenotypes
Rhabdomyosarcoma
Alveolar rhabdomyosarcoma
Disease(s) Associated with DICER1
multinodular goiter
pleuropulmonary blastoma

Mouse Phenotypes
abnormal myocardium layer morphology
abnormal myocardial fiber morphology
disorganized myocardium
dilated cardiomyopathy
decreased cardiac muscle contractility
increased cardiomyocyte apoptosis
abnormal sarcomere morphology
Availability Mouse Genotype
Dicer1tm1Bdh/Dicer1tm1Bdh
Nkx2-5tm1(cre)Rjs/Nkx2-5+  (conditional)
Dicer1tm1Smr/Dicer1tm1Smr
Tg(Myh6-cre)2182Mds/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory