About   Help   FAQ
Symbol
Name
ID
Dicer1
dicer 1, ribonuclease type III
MGI:2177178
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Euthyroid multinodular goiter
Multinodular goiter
Thyroid carcinoma
Papillary thyroid carcinoma
Disease(s) Associated with DICER1
multinodular goiter

Mouse Phenotypes
abnormal thymus morphology
abnormal thymus development
abnormal thymus epithelium morphology
abnormal thymus cortex morphology
abnormal thymus medulla morphology
athymia
decreased thymocyte number
decreased endometrial gland number
decreased ovary weight
abnormal efferent ductules of testis morphology
dilated efferent ductules of testis
Leydig cell hyperplasia
abnormal seminiferous tubule epithelium morphology
abnormal Sertoli cell morphology
ectopic Sertoli cells
small seminiferous tubules
seminiferous tubule degeneration
decreased testis weight
small testis
testis degeneration
abnormal thymus physiology
abnormal thymus involution
Availability Mouse Genotype
Dicer1tm1Bdh/Dicer1tm1Bdh
Plekha5Tg(AMH-cre)1Flor/0  (conditional)
Amhr2tm3(cre)Bhr/Amhr2+
Dicer1tm1Bdh/Dicer1tm1Bdh  (conditional)
Dicer1tm1Bdh/Dicer1tm1Bdh
H2az2Tg(Wnt1-cre)11Rth/0  (conditional)
Defb41tm1(icre)Psip/Defb41+
Dicer1tm1Bdh/Dicer1tm1Bdh  (conditional)
Dicer1tm1Mmk/Dicer1tm1Mmk
Tg(Lck-cre)1Cwi/0  (conditional)
Dicer1tm1Tara/Dicer1tm1Tara
Foxn1tm3(cre)Nrm/Foxn1+  (conditional)
Dicer1tm1Bdh/Dicer1+
H2az2Tg(Wnt1-cre)11Rth/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/15/2019
MGI 6.14
The Jackson Laboratory