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Symbol
Name
ID
Tlr8
toll-like receptor 8
MGI:2176887
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
decreased dendritic cell number
decreased B-1a cell number
decreased B-1b cell number
decreased follicular B cell number
decreased marginal zone B cell number
increased B-2 B cell number
increased marginal zone B cell number
increased spleen weight
enlarged spleen
abnormal spleen marginal zone morphology
decreased IgG1 level
increased IgG2a level
increased IgG level
increased IgM level
increased circulating interleukin-12 level
increased interleukin-6 secretion
decreased anti-insulin autoantibody level
increased anti-nuclear antigen antibody level
increased anti-double stranded DNA antibody level
glomerulonephritis
Availability Mouse Genotype
Tlr8/Tlr7tm1Vlcg/Tlr8/Tlr7tm1Vlcg
Tlr8tm1Vlcg/Tlr8tm1Vlcg

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory