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ribonucleotide reductase M2 B (TP53 inducible)
Phenotype annotations related to renal/urinary system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
renal/urinary system phenotype
abnormal glomerular capillary endothelium morphology
abnormal glomerular endothelium fenestra morphology
abnormal glomerular capillary morphology
decreased glomerular capillary number
increased kidney apoptosis
increased renal tubule apoptosis
renal tubular necrosis
increased kidney cell proliferation
abnormal urine homeostasis
increased urine protein level
abnormal renal glomerular capsule morphology
abnormal glomerular capsule parietal layer morphology
increased glomerular capsule space
abnormal podocyte morphology
podocyte foot process effacement
podocyte hypertrophy
abnormal renal glomerulus basement membrane morphology
increased renal glomerulus basement membrane thickness
abnormal renal glomerulus morphology
abnormal glomerular mesangium morphology
cortical renal glomerulopathies
renal glomerulus fibrosis
abnormal renal tubule epithelium morphology
enlarged kidney
renal tubule atrophy
abnormal renal tubule morphology
proximal convoluted tubule brush border loss
dilated renal tubules
pale kidney
abnormal kidney physiology
kidney failure
Availability Mouse Genotype
Rrm2bGt(OST85254)Lex/Rrm2bGt(OST85254)Lex *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory