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Symbol
Name
ID
Foxp2
forkhead box P2
MGI:2148705
Phenotype annotations related to behavior/neurological
Darker colors indicate more annotations
Human Phenotypes
Drooling
Feeding difficulties
Negativism
Lack of spontaneous play
Delayed early-childhood social milestone development
Impaired ability to form peer relationships
Autistic behavior
Autism
Hyperactivity
Attention deficit hyperactivity disorder
Inflexible adherence to routines
Abnormal repetitive mannerisms
Restrictive behavior
Disease(s) Associated with FOXP2
attention deficit hyperactivity disorder
autistic disorder
schizophrenia
speech-language disorder-1

Mouse Phenotypes
abnormal motor learning
decreased exploration in new environment
abnormal eating behavior
abnormal response to novel object
abnormal motor capabilities/coordination/movement
abnormal reflex
abnormal righting response
impaired righting response
decreased startle reflex
impaired coordination
decreased locomotor activity
positive geotaxis
bradykinesia
abnormal vocalization
decreased vocalization
Availability Mouse Genotype
Foxp2N549K/Foxp2N549K
Foxp2R552H/Foxp2R552H
Foxp2S321X/Foxp2S321X
Foxp2tm1Bux/Foxp2tm1Bux
Foxp2tm1Momo/Foxp2tm1Momo
Foxp2tm2.1Woen/Foxp2tm2.1Woen
Foxp2R552H/Foxp2+
Foxp2tm1Bux/Foxp2+
Foxp2tm1Momo/Foxp2+
Foxp2tm2.2Woen/Foxp2+
Foxp2tm1Sfis/Foxp2tm1.2Sfis
Edil3Tg(Sox2-cre)1Amc/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory