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Symbol
Name
ID
Pcsk9
proprotein convertase subtilisin/kexin type 9
MGI:2140260
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
homeostasis/metabolism phenotype
decreased circulating HDL cholesterol level
increased circulating HDL cholesterol level
decreased circulating LDL cholesterol level
increased circulating LDL cholesterol level
decreased circulating cholesterol level
increased circulating cholesterol level
increased circulating alkaline phosphatase level
increased bile salt level
abnormal cholesterol homeostasis
Availability Mouse Genotype
Pcsk9m1Bms/Pcsk9m1Bms
Pcsk9tm1.2Prat/Pcsk9tm1.2Prat
Pcsk9tm1Jdh/Pcsk9tm1Jdh
Pcsk9tm2b(EUCOMM)Hmgu/Pcsk9tm2b(EUCOMM)Hmgu
Pcsk9m1Bms/Pcsk9+
Tg(Apoe-Pcsk9)#Prat/?
Tg(Apoe-Pcsk9*H229A)#Prat/? *
Pcsk9tm1.1Prat/Pcsk9tm1.1Prat
Speer6-ps1Tg(Alb-cre)21Mgn/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/05/2019
MGI 6.14
The Jackson Laboratory