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Symbol
Name
ID
Lbr
lamin B receptor
MGI:2138281
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Abnormal leukocyte morphology
Neutropenia
Abnormality of neutrophils
Hyposegmentation of neutrophil nuclei
Thrombocytopenia
Giant platelets
Bone marrow hypocellularity
Extramedullary hematopoiesis
Hepatosplenomegaly
Disease(s) Associated with LBR
Greenberg dysplasia
Pelger-Huet anomaly

Mouse Phenotypes
abnormal granulocyte differentiation
abnormal neutrophil differentiation
decreased T cell proliferation
thymus hypoplasia
abnormal blood cell morphology/development
abnormal eosinophil morphology
abnormal granulocyte morphology
abnormal neutrophil morphology
abnormal lymphocyte cell number
decreased B cell number
decreased CD4-positive, alpha beta T cell number
decreased CD8-positive, alpha-beta T cell number
decreased T cell number
decreased lymphocyte cell number
decreased leukocyte cell number
abnormal lymphocyte morphology
abnormal spleen morphology
enlarged spleen
spleen hypoplasia
abnormal B cell physiology
abnormal T cell physiology
Availability Mouse Genotype
LbrGt(XE569)Byg/LbrGt(XE569)Byg
Lbric-2J/Lbric-2J
Lbric-3J/Lbric-3J
Lbric-J/Lbric-J
Lbrlym3/Lbrlym3
Lbric-J/Lbr+
Lbric-J/Lbrlym3
Lbrlym3/Lbr+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory