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Symbol
Name
ID
Sirt1
sirtuin 1
MGI:2135607
Phenotype annotations related to nervous system
Darker colors indicate more annotations

Mouse Phenotypes
decreased pituitary gland weight
small pituitary gland
abnormal pituitary gland physiology
abnormal noradrenaline level
exencephaly
decreased brain weight
increased brain size
abnormal retinal photoreceptor morphology
Availability Mouse Genotype
Sirt1tm1Fwa/Sirt1tm1Fwa
Sirt1tm1Mcby/Sirt1tm1Mcby
Sirt1tm2.1Mcby/Sirt1tm2.1Mcby
Sirt1tm1.1Cxd/Sirt1+
Sirt1tm3Fwa/Sirt1tm3Fwa
Tg(Nes-cre)1Kln/0  (conditional)
Gt(ROSA)26Sortm1(Sirt1)Ktm/Gt(ROSA)26Sor+
Tg(Pomc1-cre)16Lowl/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory