Symbol
Name
ID

Hadha
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
MGI:2135593

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes

Hypocalcemia

Elevated circulating acylcarnitine concentration

Hyperammonemia

Elevated circulating creatine kinase concentration

Elevated circulating hepatic transaminase concentration

Elevated circulating aspartate aminotransferase concentration

Hypoketotic hypoglycemia

Lactic acidosis

Hydrops fetalis

Diffuse hepatic steatosis

Myoglobinuria

Rigors

Exercise intolerance

Disease(s) Associated with HADHA

mitochondrial trifunctional protein deficiency

Mouse Phenotypes

decreased circulating carnitine level

increased circulating carnitine level

abnormal blood homeostasis

increased blood urea nitrogen level

increased circulating bilirubin level

hypoglycemia

increased circulating insulin level

increased circulating free fatty acids level

increased circulating alanine transaminase level

insulin resistance

abnormal urine homeostasis

Availability

Mouse Genotype

Hadha^tm1Jib/Hadha^tm1Jib

Hadha^tm1Jib/Hadha⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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