|
Symbol Name ID |
Ifitm5
interferon induced transmembrane protein 5 MGI:1934923 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Wormian bones |
Dentinogenesis imperfecta |
Hyperextensibility of the finger joints |
Anterior radial head dislocation |
Limited pronation/supination of forearm |
Joint hypermobility |
Hyperextensibility at elbow |
Recurrent fractures |
Abnormal pelvic girdle bone morphology |
Biconcave vertebral bodies |
Platyspondyly |
Vertebral wedging |
Osteopenia |
Hyperplastic callus formation |
| Disease(s) Associated with IFITM5 | ||||||||||||||
| osteogenesis imperfecta type 5 |
| Mouse Phenotypes | skeleton phenotype |
impaired osteoblast differentiation |
abnormal osteoblast physiology |
abnormal cranium morphology |
abnormal neurocranium morphology |
thin frontal bone |
abnormal mandible morphology |
mandible hypoplasia |
short mandible |
abnormal premaxilla morphology |
abnormal osteoclast morphology |
bowed radius |
bowed ulna |
short femur |
abnormal tibia morphology |
bowed tibia |
abnormal skeleton morphology |
abnormal clavicle morphology |
small clavicle |
clavicle hypoplasia |
abnormal long bone diaphysis morphology |
increased width of hypertrophic chondrocyte zone |
disorganized long bone epiphyseal plate |
increased long bone epiphyseal plate size |
decreased length of long bones |
abnormal ilium body morphology |
abnormal thoracic cage morphology |
abnormal rib morphology |
abnormal bone marrow cavity morphology |
decreased trabecular bone volume |
decreased bone volume |
abnormal compact bone morphology |
decreased compact bone area |
decreased compact bone thickness |
absent compact bone |
abnormal trabecular bone morphology |
decreased bone trabecula number |
increased bone trabecular spacing |
abnormal skeleton development |
increased osteoid volume |
abnormal bone ossification |
decreased bone mineralization |
delayed bone mineralization |
abnormal intramembranous bone ossification |
fragile skeleton |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||||
| Ifitm5tm1Nha/Ifitm5tm1Nha | ||||||||||||||||||||||||||||||||||||||||||||||
| Ifitm5tm1Pmof/Ifitm5tm1Pmof | * | |||||||||||||||||||||||||||||||||||||||||||||
| Ifitm5em1Pmof/Ifitm5+ | ||||||||||||||||||||||||||||||||||||||||||||||
| Tg(Col1a1-Ifitm5*)1Brle/0 | ||||||||||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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