|
Symbol Name ID |
Clcnkb
chloride channel, voltage-sensitive Kb MGI:1930643 |
| Darker colors indicate more annotations |
| Human Phenotypes | Hypomagnesemia |
Hypokalemia |
Hyponatremia |
Hypochloremia |
Hypokalemic hypochloremic metabolic alkalosis |
Hypokalemic alkalosis |
Hypokalemic metabolic alkalosis |
Dehydration |
Edema |
Recurrent fever |
Hyperchloriduria |
Renal magnesium wasting |
Increased urinary potassium |
Renal potassium wasting |
Hypernatriuria |
Hypocalciuria |
Renal salt wasting |
Chondrocalcinosis |
| Disease(s) Associated with CLCNKA | ||||||||||||||||||
| Bartter disease type 4b | ||||||||||||||||||
| Disease(s) Associated with CLCNKB | ||||||||||||||||||
| Bartter disease type 3 | ||||||||||||||||||
| Bartter disease type 4b | ||||||||||||||||||
| Gitelman syndrome | ||||||||||||||||||
| Mouse Phenotypes | increased circulating creatinine level |
alkalemia |
increased blood urea nitrogen level |
increased fasting circulating glucose level |
increased circulating cholesterol level |
increased circulating calcium level |
decreased circulating potassium level |
hypokalemia |
increased circulating alkaline phosphatase level |
increased circulating renin level |
improved glucose tolerance |
decreased circulating chloride level |
increased urine chloride ion level |
increased urine potassium level |
increased urine sodium level |
abnormal cholesterol homeostasis |
alkalosis |
abnormal urine homeostasis |
increased urine magnesium level |
decreased urine osmolality |
increased urine prostaglandin level |
decreased physiological sensitivity to xenobiotic |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||
| Clcnkatm1b(EUCOMM)Hmgu/Clcnkatm1b(EUCOMM)Hmgu | |||||||||||||||||||||||
| Clcnkatm1Suc/Clcnkatm1Suc | |||||||||||||||||||||||
| Clcnkbem1(IMPC)Mbp/Clcnkbem1(IMPC)Mbp | |||||||||||||||||||||||
| Clcnkbem1Haca/Clcnkbem1Haca | |||||||||||||||||||||||
| Clcnkbtm1.1Doel/Clcnkbtm1.1Doel | |||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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