Symbol
Name
ID

Vapb
vesicle-associated membrane protein, associated protein B and C
MGI:1928744

Phenotype annotations related to muscle

Darker colors indicate more annotations

Human Phenotypes

Calf muscle hypertrophy

Foot dorsiflexor weakness

Lower limb muscle weakness

Upper limb muscle weakness

Spasticity

EMG: neuropathic changes

Difficulty climbing stairs

Muscle spasm

Distal muscle weakness

Fatigable weakness of bulbar muscles

Fatigable weakness of swallowing muscles

Fatigable weakness of respiratory muscles

Generalized muscle weakness

Progressive muscle weakness

Proximal muscle weakness

Gowers sign

Myotonia

Skeletal muscle atrophy

Distal amyotrophy

Progressive distal muscular atrophy

Proximal amyotrophy

Spinal muscular atrophy

Progressive spinal muscular atrophy

Disease(s) Associated with VAPB

amyotrophic lateral sclerosis

amyotrophic lateral sclerosis type 8

autosomal dominant adult-onset proximal spinal muscular atrophy

Mouse Phenotypes		skeletal muscle fiber atrophy	centrally nucleated skeletal muscle fibers	hypotonia
Availability	Mouse Genotype	skeletal muscle fiber atrophy	centrally nucleated skeletal muscle fibers	hypotonia
	Vapb^tm1.1Tsud/Vapb^tm1.1Tsud
	Vapb^tm1.2Ics/Vapb^tm1.2Ics

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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