Symbol
Name
ID

Mtor
mechanistic target of rapamycin kinase
MGI:1928394

Phenotype annotations related to muscle

Darker colors indicate more annotations

Mouse Phenotypes

abnormal myocardial fiber morphology

decreased myocardial fiber size

dilated cardiomyopathy

decreased cardiac muscle contractility

decreased ventricle muscle contractility

increased cardiomyocyte apoptosis

increased skeletal muscle glycogen level

abnormal limb muscle morphology

abnormal gastrocnemius morphology

abnormal soleus morphology

abnormal tibialis anterior morphology

abnormal muscle morphology

abnormal sarcomere morphology

abnormal skeletal muscle fiber morphology

centrally nucleated skeletal muscle fibers

skeletal muscle fiber degeneration

decreased skeletal muscle weight

abnormal diaphragm morphology

skeletal muscle degeneration

abnormal muscle physiology

abnormal muscle contractility

abnormal muscle relaxation

increased muscle fatigability

Availability

Mouse Genotype

Mtor^tm1.1Clyn/Mtor⁺

Mtor^tm1.1Gcon/Mtor^tm1.1Gcon
A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/A1cf⁺ (conditional)

Mtor^tm1.2Koz/Mtor^tm1.2Koz
Tg(ACTA1-cre)79Jme/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23