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Symbol
Name
ID
Huwe1
HECT, UBA and WWE domain containing 1
MGI:1926884
Phenotype annotations related to cellular
Darker colors indicate more annotations

Mouse Phenotypes
oligozoospermia
abnormal spermatocyte morphology
abnormal spermatogonia morphology
decreased male germ cell number
increased B cell apoptosis
increased male germ cell apoptosis
increased testis apoptosis
decreased B cell proliferation
abnormal neuronal precursor proliferation
abnormal male germ cell physiology
Availability Mouse Genotype
Cd79atm1(cre)Reth/Cd79a+
Huwe1tm1.1Mak/Y  (conditional)
Huwe1tm1Alas/Y
Tg(Nes-cre)1Kag/0  (conditional)
Huwe1tm1Alas/Y
Tg(Stra8-icre)1Reb/0  (conditional)
Huwe1tm1Alas/Y
Tg(Spo11-cre)1Rsw/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory