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Symbol
Name
ID
Nckap1l
NCK associated protein 1 like
MGI:1926063
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
heart inflammation
impaired neutrophil chemotaxis
decreased T cell proliferation
impaired macrophage phagocytosis
impaired neutrophil phagocytosis
abnormal thymus lobule morphology
thymus hypoplasia
abnormal lymphopoiesis
abnormal CD4-positive T cell differentiation
increased double-negative T cell number
decreased double-positive T cell number
increased neutrophil cell number
decreased mature B cell number
decreased B cell number
decreased NK cell number
increased effector memory CD4-positive, alpha-beta T cell number
decreased CD4-positive, alpha beta T cell number
decreased central memory CD8 positive, alpha-beta T cell number
increased effector memory CD8-positive, alpha-beta T cell number
decreased CD8-positive, naive alpha-beta T cell number
decreased CD8-positive, alpha-beta T cell number
increased CD8-positive, alpha-beta T cell number
decreased alpha-beta T cell number
increased alpha-beta T cell number
decreased mature gamma-delta T cell number
abnormal regulatory T cell number
decreased lymphocyte cell number
increased leukocyte cell number
spleen hyperplasia
increased circulating interleukin-17 level
increased circulating interleukin-6 level
abnormal immune system organ morphology
lymph node hypoplasia
increased interleukin-17 secretion
increased interleukin-6 secretion
increased tumor necrosis factor secretion
liver inflammation
lung inflammation
Availability Mouse Genotype
Nckap1lm1Btlr/Nckap1lm1Btlr
Nckap1lm1Iri/Nckap1lm1Iri

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory