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Symbol
Name
ID

Rspo2
R-spondin 2
MGI:1922667

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Human Phenotypes	Micrognathia	Microretrognathia	Amelia
Disease(s) Associated with RSPO2
tetraamelia syndrome 2

Mouse Phenotypes

short Meckel's cartilage

abnormal temporal bone squamous part morphology

abnormal tooth development

growth retardation of incisors

abnormal mandibular angle morphology

small mandibular condyloid process

absent mandibular coronoid process

small mandible

short mandible

abnormal maxilla morphology

abnormal maxillary shelf morphology

maxillary shelf hypoplasia

abnormal maxillary zygomatic process morphology

small maxilla

decreased palatine bone horizontal plate size

abnormal zygomatic bone morphology

abnormal phalanx morphology

brachyphalangia

absent radius

absent fibula

short fibula

absent tibia

short tibia

short metatarsal bones

abnormal laryngeal cartilage morphology

arytenoid and cricoid cartilage fusion

abnormal tracheal cartilage morphology

abnormal bone ossification

Availability

Mouse Genotype

Rspo2^ftls/Rspo2^ftls

Rspo2^tm1Hoka/Rspo2^tm1Hoka

Rspo2^tm1Nuv/Rspo2^tm1Nuv

Rspo2^tm1Suda/Rspo2^tm1Suda

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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