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Symbol
Name
ID

Mgme1
mitochondrial genome maintenance exonuclease 1
MGI:1921778

Phenotype annotations related to cellular

Darker colors indicate more annotations

Human Phenotypes	Decreased mitochondrial number	Decreased activity of mitochondrial complex I	Decreased activity of mitochondrial complex IV
Disease(s) Associated with MGME1
mitochondrial DNA depletion syndrome 11

Mouse Phenotypes		decreased mitochondrial DNA content	abnormal mitochondrial physiology
Availability	Mouse Genotype	decreased mitochondrial DNA content	abnormal mitochondrial physiology
	Mgme1^tm1.2Lrsn/Mgme1^tm1.2Lrsn
	Mgme1^tm1.1Lrsn/Mgme1^tm1.1Lrsn Tg(Ckmm-cre)5Khn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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