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Symbol
Name
ID

Morc2a
microrchidia 2A
MGI:1921772

Phenotype annotations related to muscle

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Congenital finger flexion contractures

Flexion contracture of finger

Distal lower limb muscle weakness

Intrinsic hand muscle atrophy

Hand muscle weakness

Proximal upper limb amyotrophy

Proximal muscle weakness in upper limbs

Upper limb amyotrophy

Foot dorsiflexor weakness

Proximal muscle weakness in lower limbs

Upper limb muscle weakness

Wrist drop

Limb-girdle muscle atrophy

Limb-girdle muscle weakness

Joint contracture of the hand

Distal upper limb muscle weakness

Hypertonia

Hypotonia

Generalized hypotonia

Functional motor deficit

Difficulty running

Difficulty walking

Muscle spasm

Diaphragmatic paralysis

Distal muscle weakness

Generalized muscle weakness

Neck muscle weakness

Proximal muscle weakness

Respiratory insufficiency due to muscle weakness

Distal amyotrophy

Distal lower limb amyotrophy

Lower limb amyotrophy

Spinal muscular atrophy

Disease(s) Associated with MORC2

Charcot-Marie-Tooth disease axonal type 2Z

Mouse Phenotypes

muscle phenotype

abnormal pectinate muscle morphology

abnormal masticatory muscle morphology

abnormal eye muscle morphology

absent eye muscles

skeletal muscle fiber atrophy

abnormal diaphragm morphology

diaphragmatic hernia

abnormal infrahyoid muscle connection

absent digastric muscle

skeletal muscle atrophy

Availability

Mouse Genotype

Morc2a^{em1(IMPC)Wtsi}/Morc2a^{em1(IMPC)Wtsi}

Morc2a^em1Snupy/Morc2a⁺

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Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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