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Symbol
Name
ID

Esco2
establishment of sister chromatid cohesion N-acetyltransferase 2
MGI:1919238

Phenotype annotations related to cellular

Darker colors indicate more annotations

Human Phenotypes	Premature separation of centromeric heterochromatin
Disease(s) Associated with ESCO2	Premature separation of centromeric heterochromatin
Roberts syndrome

Mouse Phenotypes		abnormal cell nucleus morphology	abnormal chromosome morphology	abnormal mitosis	increased mitotic index	increased neuron apoptosis	abnormal neuronal precursor proliferation	decreased cell proliferation
Availability	Mouse Genotype	abnormal cell nucleus morphology	abnormal chromosome morphology	abnormal mitosis	increased mitotic index	increased neuron apoptosis	abnormal neuronal precursor proliferation	decreased cell proliferation
	Esco2^tm1.2Ge/Esco2^tm1.2Ge
	Esco2^tm1.1Ge/Esco2^tm1.1Ge Tg(CAG-cre/Esr1*)5Amc/0 (conditional)
	Emx1^tm1(cre)Krj/Emx1⁺ Esco2^tm1.1Ge/Esco2^tm1.1Ge (conditional)
	Esco2^tm1.1Ge/Esco2^tm1.1Ge Ndor1^{Tg(UBC-cre/ERT2)1Ejb}/Ndor1⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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