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Symbol
Name
ID

Tmprss6
transmembrane serine protease 6
MGI:1919003

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Elevated circulating hepcidin concentration
Disease(s) Associated with TMPRSS6	Elevated circulating hepcidin concentration
microcytic anemia

Mouse Phenotypes		decreased heart iron level	decreased pancreas iron level	decreased spleen iron level	increased fasting circulating glucose level	increased circulating calcium level	decreased circulating iron level	increased circulating unsaturated transferrin level	abnormal iron homeostasis	abnormal iron level	decreased liver iron level
Availability	Mouse Genotype	decreased heart iron level	decreased pancreas iron level	decreased spleen iron level	increased fasting circulating glucose level	increased circulating calcium level	decreased circulating iron level	increased circulating unsaturated transferrin level	abnormal iron homeostasis	abnormal iron level	decreased liver iron level
	Tmprss6^hem8/Tmprss6^hem8
	Tmprss6^m2Btlr/Tmprss6^m2Btlr
	Tmprss6^m3Btlr/Tmprss6^m3Btlr
	Tmprss6^msk/Tmprss6^msk
	Tmprss6^{tm1b(EUCOMM)Wtsi}/Tmprss6^{tm1b(EUCOMM)Wtsi}
	Tmprss6^tm1Dgen/Tmprss6^tm1Dgen
	Tmprss6^tm1Otin/Tmprss6^tm1Otin
	Tmprss6^hem8/Tmprss6^tm1Dgen
	Tmprss6^tm1Dgen/Tmprss6⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23