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G protein-coupled receptor 15
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
increased susceptibility to induced colitis
decreased double-negative T cell number
decreased CD4-positive, alpha beta T cell number
increased CD8-positive, alpha-beta T cell number
decreased regulatory T cell number
abnormal regulatory T cell physiology
increased interferon-gamma secretion
increased interleukin-17 secretion
increased susceptibility to bacterial infection
increased susceptibility to bacterial infection induced morbidity/mortality
Availability Mouse Genotype
Gpr15tm1.1Litt/Gpr15tm1.1Litt *! ! !

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory