|
Symbol Name ID |
Wls
wntless WNT ligand secretion mediator MGI:1915401 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Sparse scalp hair |
Preauricular skin tag |
Sparse eyebrow |
Sparse lateral eyebrow |
Wide intermamillary distance |
Hypoplastic toenails |
Hyperextensible skin |
Sacral dimple |
| Disease(s) Associated with WLS | ||||||||
| Zaki syndrome |
| Mouse Phenotypes | integument phenotype |
increased keratinocyte proliferation |
epidermal spongiosis |
impaired skin barrier function |
skin inflammation |
abnormal hair growth |
sparse hair |
thin hypodermis |
abnormal hair follicle morphology |
abnormal hair follicle development |
decreased hair follicle number |
hair follicle degeneration |
abnormal hair cycle catagen phase |
abnormal dermal layer morphology |
thin dermal layer |
abnormal epidermal layer morphology |
abnormal keratinocyte morphology |
abnormal skin appearance |
flaky skin |
reddish skin |
scaly skin |
thin skin |
abnormal skin physiology |
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| Availability | Mouse Genotype | |||||||||||||||||||||||
| Wlstm1.1Arte/Wlstm1.1Arte Krt14tm1(cre)Wbm/Krt14+ (conditional) |
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| Wlstm1.1Arte/Wlstm1.1Arte Tg(Foxn1-cre)1Tbo/0 (conditional) |
* | |||||||||||||||||||||||
| Tg(KRT5-rtTA)#Glk/0 Tg(tetO-cre)1Jaw/0 Wlstm1.1Lan/Wlstm1.1Lan (conditional) |
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| Tg(Krt1-15-cre/PGR*)22Cot/0 Wlstm1.1Lan/Wlstm1.1Lan (conditional) |
* | |||||||||||||||||||||||
| Wlstm1Xzg/Wlstm1Xzg Tg(Msx2-cre)5Rem/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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