Symbol
Name
ID

Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
MGI:1915384

Phenotype annotations related to behavior/neurological

Darker colors indicate more annotations

Human Phenotypes	Autistic behavior	Hypernasal speech
Disease(s) Associated with UPF3B	Autistic behavior	Hypernasal speech
syndromic X-linked intellectual disability 14

Mouse Phenotypes

impaired contextual conditioning behavior

impaired cued conditioning behavior

decreased freezing behavior

decreased startle reflex

limb grasping

increased vertical activity

hyperactivity

abnormal sleep duration

abnormal sleep pattern

decreased slow-wave sleep duration

decreased frequency of paradoxical sleep

Availability

Mouse Genotype

Upf3b^em1(IMPC)Tcp/Upf3b^em1(IMPC)Tcp

Upf3b^{Gt(IST14619B5)Tigm}/Upf3b^{Gt(IST14619B5)Tigm}

Upf3b^{Gt(IST14619B5)Tigm}/Upf3b⁺

Upf3b^em1(IMPC)Tcp/Y

Upf3b^{Gt(IST14619B5)Tigm}/Y

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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