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Symbol
Name
ID
Rubcn
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
MGI:1915160
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
increased neutrophil cell number
increased CD8-positive, alpha-beta T cell number
increased lymphocyte cell number
increased monocyte cell number
abnormal spleen morphology
increased IgG level
abnormal macrophage physiology
abnormal circulating chemokine level
increased circulating interleukin-1 beta level
decreased circulating interleukin-10 level
increased circulating interleukin-12b level
increased circulating interleukin-6 level
increased susceptibility to systemic lupus erythematosus
increased autoantibody level
increased anti-nuclear antigen antibody level
increased anti-double stranded DNA antibody level
glomerulonephritis
Availability Mouse Genotype
Rubcnem1Dgre/Rubcnem1Dgre *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory