Symbol Name ID |
Slc39a8
solute carrier family 39 (metal ion transporter), member 8 MGI:1914797 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Decreased activity of mitochondrial complex II |
Decreased activity of mitochondrial complex IV |
Decreased activity of the pyruvate dehydrogenase complex |
Hypomanganesemia |
Abnormal blood zinc concentration |
Increased CSF lactate |
Type II transferrin isoform profile |
Disease(s) Associated with SLC39A8 | |||||||
congenital disorder of glycosylation type IIn |
Mouse Phenotypes | homeostasis/metabolism phenotype |
increased insulin secretion |
abnormal homeostasis |
decreased circulating glucose level |
increased circulating glucose level |
increased circulating insulin level |
increased circulating triglyceride level |
increased circulating phosphate level |
edema |
increased urine glucose level |
insulin resistance |
abnormal zinc level |
decreased brain zinc level |
increased circulating zinc level |
|
Availability | Mouse Genotype | ||||||||||||||
Slc39a8em1Xijl/Slc39a8em1Xijl | * | ||||||||||||||
Slc39a8tm1.1Brvo/Slc39a8tm1.1Brvo | * | ||||||||||||||
Slc39a8tm1.2Mrl/Slc39a8tm1.2Mrl | |||||||||||||||
Slc39a8tm1b(EUCOMM)Wtsi/Slc39a8+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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