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Symbol
Name
ID
Agpat2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
MGI:1914762
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Hypertriglyceridemia
Insulin-resistant diabetes mellitus at puberty
Hyperinsulinemia
Decreased serum leptin
Disease(s) Associated with AGPAT2
congenital generalized lipodystrophy type 1

Mouse Phenotypes
homeostasis/metabolism phenotype
increased circulating glucose level
hyperglycemia
increased circulating insulin level
decreased circulating leptin level
increased circulating cholesterol level
decreased circulating free fatty acid level
increased circulating triglyceride level
decreased body temperature
abnormal gas homeostasis
increased carbon dioxide production
increased oxygen consumption
decreased respiratory quotient
abnormal glucose homeostasis
improved glucose tolerance
insulin resistance
abnormal lipid homeostasis
abnormal fatty acid level
abnormal phospholipid level
increased liver triglyceride level
Availability Mouse Genotype
Agpat2Gt(OST438470)Lex/Agpat2Gt(OST438470)Lex
Agpat2tm1Garg/Agpat2tm1Garg *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory