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Symbol Name ID |
Cul4a
cullin 4A MGI:1914487 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | abnormal sperm flagellum morphology |
azoospermia |
oligozoospermia |
abnormal sperm head morphology |
abnormal spermatid morphology |
abnormal spermatocyte morphology |
multinucleated giant male germ cells |
abnormal centrosome morphology |
abnormal cell cycle checkpoint function |
increased cellular sensitivity to ultraviolet irradiation |
increased enterocyte apoptosis |
increased male germ cell apoptosis |
asthenozoospermia |
decreased fibroblast proliferation |
decreased hepatocyte proliferation |
abnormal DNA repair |
abnormal double-strand DNA break repair |
abnormal DNA replication |
chromosomal instability |
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| Availability | Mouse Genotype | |||||||||||||||||||
| Cul4atm1.2Pra/Cul4atm1.2Pra | ||||||||||||||||||||
| Cul4atm1.2Pz/Cul4atm1.2Pz | ||||||||||||||||||||
| Cul4a/Pcid2tm2Ktc/Cul4a/Pcid2tm2Ktc Tg(Mx1-cre)1Cgn/0 (conditional) |
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| Cul4atm1.1Pra/Cul4atm1.1Pra (conditional) | ||||||||||||||||||||
| Cul4atm1.1Pra/Cul4atm1.1Pra Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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