Symbol
Name
ID

Sar1b
secretion associated Ras related GTPase 1B
MGI:1913647

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Decreased LDL cholesterol concentration	Hypocholesterolemia	Hypertriglyceridemia	Hypotriglyceridemia	Hypoalbuminemia	Elevated circulating hepatic transaminase concentration	Abnormality of vitamin metabolism	Hepatic steatosis	Increased hepatocellular lipid droplets
Disease(s) Associated with SAR1B
chylomicron retention disease

Mouse Phenotypes

abnormal intestinal lipid absorption

steatorrhea

decreased circulating HDL cholesterol level

abnormal circulating non-HDL cholesterol level

decreased circulating LDL cholesterol level

decreased circulating cholesterol level

decreased circulating free fatty acids level

increased circulating free fatty acids level

decreased circulating triglyceride level

decreased circulating alanine transaminase level

increased liver cholesterol level

abnormal lipid metabolism

decreased lipogenesis

Availability

Mouse Genotype

Sar1b^em1Emle/Sar1b⁺

Sar1b^em2Emle/Sar1b⁺

Sar1b^{tm1a(EUCOMM)Wtsi}/Sar1b⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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