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Symbol
Name
ID

Sostdc1
sclerostin domain containing 1
MGI:1913292

Phenotype annotations related to skeleton

!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Mouse Phenotypes

decreased chondrocyte proliferation

increased osteoblast proliferation

abnormal osteoblast physiology

decreased cranium height

decreased cranium width

abnormal tooth morphology

supernumerary incisors

abnormal molar crown morphology

abnormal molar cusp morphology

fused molars

supernumerary molars

abnormal enamel knot morphology

supernumerary teeth

short mandible

decreased osteoclast cell number

increased bone mineral content

increased bone mineral density

increased trabecular bone volume

increased osteoblast cell number

increased bone mass

abnormal bone ossification

abnormal bone mineralization

Availability

Mouse Genotype

Sostdc1^shk/Sostdc1^shk

!

Sostdc1^tm1Myan/Sostdc1^tm1Myan

Sostdc1^tm1Nit/Sostdc1^tm1Nit

Sostdc1^tm1Snd/Sostdc1^tm1Snd

!

Sostdc1^tm2Myan/Sostdc1^tm2Myan

Sostdc1^tm2Snd/Sostdc1^tm2Snd

!

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23