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Symbol
Name
ID
Dact1
dishevelled-binding antagonist of beta-catenin 1
MGI:1891740
Phenotype annotations related to limbs/digits/tail
Darker colors indicate more annotations
Human Phenotypes
Broad thumb
Partial duplication of thumb phalanx
Preaxial hand polydactyly
Triphalangeal thumb
Clinodactyly of the 5th toe
Aplasia/Hypoplasia of the 3rd toe
1-2 toe syndactyly
2-3 toe syndactyly
3-4 toe syndactyly
4-5 toe syndactyly
2-4 finger syndactyly
3-4 finger syndactyly
Pseudoepiphyses of second metacarpal
Short metatarsal
Metatarsal synostosis
Talipes
Disease(s) Associated with DACT1
Townes-Brocks syndrome

Mouse Phenotypes
sirenomelia
abnormal tail bud morphology
decreased caudal vertebrae number
short tail
Availability Mouse Genotype
Dact1tm1.1Bnrc/Dact1tm1.1Bnrc
Dact1tm1Yegc/Dact1tm1Yegc

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory