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Symbol
Name
ID
Lgr4
leucine-rich repeat-containing G protein-coupled receptor 4
MGI:1891468
Phenotype annotations related to vision/eye
Darker colors indicate more annotations

Mouse Phenotypes
corneal vascularization
increased incidence of corneal inflammation
retinal ganglion cell degeneration
abnormal anterior eye segment morphology
abnormal iridocorneal angle
abnormal canal of Schlemm morphology
hypoplastic trabecular meshwork
ciliary body hypoplasia
iris stroma hypoplasia
mydriasis
iris hypoplasia
anterior iris synechia
abnormal cornea morphology
decreased cornea thickness
decreased corneal stroma thickness
abnormal corneal epithelium morphology
abnormal corneal stroma morphology
corneal deposits
corneal opacity
abnormal lens morphology
disorganized secondary lens fibers
cataract
small lens
microphthalmia
eyelids open at birth
abnormal retina morphology
thin retinal inner nuclear layer
disorganized retinal inner nuclear layer
thin retinal outer nuclear layer
disorganized retinal outer nuclear layer
Availability Mouse Genotype
Lgr4Gt(LST020)Byg/Lgr4Gt(LST020)Byg
Lgr4tm1.2Knis/Lgr4tm1.2Knis
Lgr4tm1.1Knis/Lgr4tm1.1Knis
Tg(KRT5-cre)1Tak/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory