Symbol
Name
ID

Lgr4
leucine-rich repeat-containing G protein-coupled receptor 4
MGI:1891468

Phenotype annotations related to vision/eye

Darker colors indicate more annotations

Mouse Phenotypes

corneal vascularization

increased incidence of corneal inflammation

retina ganglion cell degeneration

abnormal anterior eye segment morphology

abnormal iridocorneal angle

abnormal canal of Schlemm morphology

hypoplastic trabecular meshwork

ciliary body hypoplasia

iris stroma hypoplasia

mydriasis

iris hypoplasia

anterior iris synechia

abnormal cornea morphology

decreased cornea thickness

decreased corneal stroma thickness

abnormal corneal epithelium morphology

decreased corneal epithelium thickness

corneal epithelium hypoplasia

abnormal corneal stroma morphology

corneal deposits

corneal opacity

abnormal lens morphology

disorganized secondary lens fibers

cataract

small lens

microphthalmia

eyelids open at birth

abnormal retina morphology

thin retina inner nuclear layer

disorganized retina inner nuclear layer

thin retina outer nuclear layer

disorganized retina outer nuclear layer

Availability

Mouse Genotype

Lgr4^{Gt(LST020)Byg}/Lgr4^{Gt(LST020)Byg}

Lgr4^tm1.2Knis/Lgr4^tm1.2Knis

Lgr4^tm1.1Knis/Lgr4^tm1.1Knis
Tg(KRT5-cre)1Tak/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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