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Symbol
Name
ID
Lpin1
lipin 1
MGI:1891340
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Hyperkalemia
Elevated serum creatine kinase
Fever
Myoglobinuria
Exercise-induced myoglobinuria
Recurrent myoglobinuria
Disease(s) Associated with LPIN1
myoglobinuria

Mouse Phenotypes
decreased insulin secretion
increased circulating glucose level
increased circulating insulin level
decreased circulating leptin level
increased circulating HDL cholesterol level
decreased circulating LDL cholesterol level
decreased circulating VLDL cholesterol level
increased circulating triglyceride level
increased circulating VLDL triglyceride level
abnormal enzyme/coenzyme level
abnormal respiratory quotient
abnormal glucose homeostasis
abnormal gluconeogenesis
impaired glucose tolerance
increased glycogen level
insulin resistance
abnormal lipid homeostasis
abnormal cholesterol homeostasis
increased cholesterol level
abnormal lipid level
decreased fatty acid level
increased fatty acid level
abnormal phospholipid level
abnormal triglyceride level
increased liver triglyceride level
decreased triglyceride level
increased triglyceride level
abnormal metabolism
abnormal enzyme/coenzyme activity
decreased hormone-sensitive lipase activity
decreased lipoprotein lipase activity
decreased triglyceride lipase activity
Availability Mouse Genotype
Lpin1fld-2J/Lpin1fld-2J
Lpin1fld/Lpin1fld

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory