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Symbol
Name
ID
Lrat
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
MGI:1891259
Phenotype annotations related to vision/eye
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Retinal dystrophy
Rod-cone dystrophy
Optic disc pallor
Decreased light- and dark-adapted electroretinogram amplitude
Undetectable electroretinogram
Nystagmus
Nyctalopia
Photophobia
Reduced visual acuity
Congenital blindness
Disease(s) Associated with LRAT
Leber congenital amaurosis 14

Mouse Phenotypes
vision/eye phenotype
abnormal retinal photoreceptor morphology
short photoreceptor outer segment
abnormal retinal cone cell outer segment morphology
retinal cone cell degeneration
retinal rod cell degeneration
retinal photoreceptor degeneration
thin retinal outer nuclear layer
abnormal eye electrophysiology
Availability Mouse Genotype
Lrattm1.1Bok/Lrattm1.1Bok
Lrattm1Kpal/Lrattm1Kpal
Lrattm1Kpal/Lrat+ *
Lrattm1Bok/Lrattm1Bok
Tg(Tyrp1-cre)1Ipc/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory