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Symbol
Name
ID
Zfp423
zinc finger protein 423
MGI:1891217
Phenotype annotations related to nervous system
Darker colors indicate more annotations
Human Phenotypes
Cerebellar vermis hypoplasia
Disease(s) Associated with ZNF423
nephronophthisis 14

Mouse Phenotypes
abnormal cerebellar granule cell precursor proliferation
abnormal cerebellum development
reduced cerebellar foliation
abnormal cerebellar plate morphology
decreased hindbrain size
decreased brain size
enlarged fourth ventricle
enlarged lateral ventricles
dilated fourth ventricle
dilated lateral ventricles
abnormal choroid plexus morphology
abnormal interventricular foramen morphology
abnormal corpus callosum morphology
absent corpus callosum
abnormal hippocampal commissure morphology
abnormal medulla oblongata morphology
abnormal forebrain morphology
small thalamus
abnormal hippocampus morphology
abnormal telencephalon morphology
abnormal olfactory bulb morphology
small olfactory bulb
abnormal cerebellum morphology
abnormal cerebellar cortex morphology
abnormal cerebellum lateral hemisphere morphology
abnormal Purkinje cell dendrite morphology
decreased Purkinje cell number
ectopic Purkinje cell
abnormal cerebellum vermis morphology
absent cerebellum vermis
cerebellum vermis hypoplasia
absent cerebellum
small cerebellum
cerebellum hypoplasia
abnormal olfactory nerve morphology
Availability Mouse Genotype
Zfp423Gt(XB409)Byg/Zfp423Gt(XB409)Byg
Zfp423nur12/Zfp423nur12
Zfp423tm1.2Ngc/Zfp423tm1.2Ngc
Zfp423tm1Reed/Zfp423tm1Reed
Zfp423Gt(XH542)Byg/Zfp423tm1.2Ngc
Zfp423nur12/Zfp423Gt(XH542)Byg

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory