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Symbol
Name
ID
Sit1
suppression inducing transmembrane adaptor 1
MGI:1889342
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
increased T cell proliferation
thymus hyperplasia
abnormal T cell differentiation
abnormal T-helper 1 cell differentiation
increased double-positive T cell number
abnormal lymphocyte cell number
decreased CD4-positive, alpha beta T cell number
decreased CD8-positive, alpha-beta T cell number
increased mature gamma-delta T cell number
lymph node hypoplasia
abnormal cytokine secretion
increased interferon-gamma secretion
increased interleukin-2 secretion
increased tumor necrosis factor secretion
increased susceptibility to experimental autoimmune encephalomyelitis
Availability Mouse Genotype
Sit1tm1Lsmn/Sit1tm1Lsmn

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory